The San Francisco 49ers (4-0) are the lone undefeated team in the NFC, and only one of two left in the entire NFL. They’re fresh off a commanding victory against the Cleveland Browns on Monday night, but the test Week 6 won’t be any easier. Quarterback Jimmy Garoppolo and the Niners will travel to Los Angeles to face Jared Goff and the 3-2 Rams, a squad that has suddenly lost two games in a row.
This is a huge matchup, with both teams playing in the NFC West and the Rams needing a victory to keep pace with San Francisco and the Seattle Seahawks (4-1).
Time: Sunday, 4:05 p.m. ET, Los Angeles Memorial Coliseum, Los Angeles
TV: FOX (Dick Stockton, Mark Schlereth)
betMGM line: Rams by 3
The 49ers pass rush showed it’s a force that can alter games, after defensive end Nick Bosa sacked Browns quarterback Baker Mayfield twice and San Francisco sacked Mayfield four times overall. The matchup to watch, though, is the Niners rushing attack versus the Rams rushing defense. San Francisco leads the NFL with 200 rushing yards per game, while L.A. is in the middle of the pack, ranking 15th in rushing yards allowed with 106.8 a game.
Defensively, the Rams' pass rush has underwhelmed this season after defensive tackle Aaron Donald and company dominated in 2018. Donald has just one sack through five games, and it may be tough for him to add another. Garoppolo ranks second in the NFL in time to throw, getting rid of the ball in an average of 2.45 seconds after the snap.