No details have been released on potential injuries, but one pilot is feared dead.
The plane, thought to be a Canadair craft, crashed into a hillside on the island.
It then bursts into flames.
According to local media, a helicopter has been dispatched to the hillside following the crash.
Several ambulances have rushed to the scene.
Thousands of tourists have been evacuated from Greece as dangerous wildfires spread by high winds continue to ravage the country.
Up to 10,000 British tourists were affected and a number of repatriation flights have brought them back to the UK.
The final repatriation flight planned by Tui is set to take off on Tuesday morning.
What was the plane that crashed?
The aircraft is thought to be a Canadair CL-415.
It can scoop up to 6,140 litres of water from a nearby water source, mix it with a chemical foam if needed, and drop it on a fire to quell flames.
Derived from its predecessor’s nickname, the aircraft has acquired the name ‘Super Scooper’ in light of its greatly enhanced performance as a water bomber and fire suppresser.
Brightly coloured in yellow and red, it has also been used in search and rescue operations.
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